Generally How can I deal with friends who have 'tricky' personalities or are difficult to deal with?

This is a pretty general question- but otherwise i would have to make lots of different questions. Tell me how you dealt with some difficult friends and give me some advice please, thanks.Generally How can I deal with friends who have 'tricky' personalities or are difficult to deal with?
I have went through this you just need to move on with your life or let them know how you feel. Friends will come and go throughout your life and true one will b there until the end. Always rely on yourself.Generally How can I deal with friends who have 'tricky' personalities or are difficult to deal with?
First response is find new friends. Friends like this get tireing quickly, as they seem to take things the wrong way, are sensitive to every little thing etc.